ea0070aep790 | Reproductive and Developmental Endocrinology | ECE2020
Orsolini Francesca
, Ferrarini Eleonora
, Agretti Patrizia
, De Marco Giuseppina
, Di Cosmo Caterina
, Benelli Elena
, Fruzzetti Franca
, Tonacchera Massimo
Background: Premature ovarian insufficiency (POI) is an ovarian defect characterized from primary or secondaryamenorrhea, high levels of FSH (> 25 UI/l) and low levels of estrogen, which occurs before age 40.Objective: The aim of the study was to evaluate the clinical features and genetic causes of a group of 68 patients with POI.Methods: We performed anamnestic and clinical evaluation, hormonal and autoimmunity assessment, pel...